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Search Result

Search Results for " anxiolytic activity "

20

Compounds

Cat No. Product Name Synonyms Targets
T1292 Tiapride hydrochloride Dopamine Receptor
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...
T2599 Pirenperone 5-HT Receptor
Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action.
T13318 VU0650786 GluR
VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents.
T5135 Flupentixol dihydrochloride Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride Dopamine Receptor
Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.
T28662 Saripidem SL-850274,SL-85.0274,SL850274,SL85.0274 Others
Saripidem (SL-85.0274) is a compound with anxiolytic activity.
T28303 Pazinaclone A-77000,DN-2327,DN2327,DN 2327,A 77000,A77000 GABA Receptor
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.
T23007 MM 77 dihydrochloride FITC-Dextran (60842-46-8 MW 4000) 5-HT Receptor
MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.
T12847 SB-616234-A SB-616234A 5-HT Receptor
SB-616234A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.
T27001 CGS8216 CGS 8216,CGS-8216 Others
CGS8216 is a benzodiazepine receptor antagonist that shows analgesic activity at high doses.CGS8216 has anxiolytic activity and may be used to study immune system disorders.
T34896 Tofisopam Emandaxin,Grandaxin Others
Tofisopam (Grandaxin) is a 2,3-benzodiazepine compound with anxiolytic activity that can be taken orally.
T12998 SR10067 Others , Autophagy
SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbα/β(IC50 of 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively),has anxiolytic activity.
T27262 Enciprazine WY-48624,D-3112,WY48624,WY 48624,D 3112,D3112 5-HT Receptor
Enciprazine (D-3112) has anxiolytic activity with high affinity for 5-HT1A receptor and ADRA1, which can be used for the treatment of anxiety disorders and can be used to study depression.
T2359 ANA-12 ANA 12,ANA12 Trk receptor
ANA-12 is a potent and selective TrkB antagonist with anxiolytic and antidepressant activity in mice.
T28887 Suriclone RP-31264,RP31264,RP 31264 GABA Receptor
Suriclone (RP 31264) is a selective cyclic pyrrolidone analog with sedative and anxiolytic activity, but not significant sedative effects.Suriclone shows its effects by modulating GABA-A receptors.
T23470 Tracazolate hydrochloride Tracazolate (hydrochloride) GABA Receptor
Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity. Tracazolate hydrochloride potentiates α1β1γ2s and α1β3γ2 with EC50s of 13.2 μM and...
T68142 Serazapine 5-HT Receptor
Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
T13329 Vofopitant GR 205171 Neurokinin receptor
Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).
T83651 AC-263093 Neuropeptide Y Receptor
AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus.
T61816 EMD 56551 5-HT Receptor
EMD 56551 is a selective small molecule 5-HT1A receptor agonist with anxiolytic activity for the study of anxiety disorders.
T23509 VU 0285683 GluR
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
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